Acta Paediatr 85 (1996): 1389-90, 28. constipation. That benefit has not been established. Havranek JM, Wolfsen AR, Warnke GA, Phillips PS "Monotherapy with ezetimibe causing myopathy." Medically reviewed by Drugs.com. Am J Med 94 (1993): 109-10, 18. Krasovec M, Elsner P, Burg G "Generalized eczematous skin rash possibly due to HMG-CoA reductase inhibitors." "Product Information. All I can say is my body wasn’t in this kind of pain before starting Zetia. They found that short-term confusion, memory loss, and poorer problem solving and information processing are common after bypass surgery, but are usually temporary and reversible. J Clin Endocrinol Metab 86 (2001): 4556-9, 23. Muscle abnormalities in four patients taking statins to treat unfavorable cholesterol levels." In one study, this led to the discontinuation of simvastatin in 0.6% of patients. 2. There are other ways to deal with health issues. What are the CPR Steps For Adults, Children and Infants? 9. Inhibition of matrix metalloproteinases has been suggested as the contributing factor in the development of tendon rupture. Vytorin (ezetimibe-simvastatin)." Memory loss also can be a side effect of other medicines, such as steroids, anti-depressants, sleeping pills, and pain medications. Experience with HMG-CoA reductase inhibitors indicates that concomitant use with gemfibrozil, niacin, cyclosporine, or erythromycin may increase the incidence and the severity of musculoskeletal side effects. What Causes High Triglycerides and is it Dangerous? A meta-analysis of large randomized clinical trials." Common (1% to 10%): Diarrhea, abdominal pain, nausea, Common (1% to 10%): Constipation, nausea, flatulence, diarrhea, dyspepsia, abdominal pain, pancreatitis, anorexia, vomiting, gastritis, Very rare (less than 0.01%): Protein losing enteropathy[Ref]. Some side effects may not be reported. Omar MA, Wilson JP "FDA adverse event reports on statin-associated rhabdomyolysis." Here are some of the other problems those taking Zetia have faced: allergic reactions including facial and throat swelling which may cause difficulty in breathing or swallowing. Alternatives: If you are being treated for RLS, ask your doctor or pharmacist whether one of your prescription or over-the-counter medications may be the trigger. Schering-Plough Corporation, Kenilworth, NJ. … I took myself off statins which resulted in significant increase in lipids and bad cholesterol. All About Congestive Heart Failure – Symptoms, Causes & Treatment. This is not a complete list of side effects and others may occur. Sinzinger H, Wolfram R, Peskar BA "Muscular side effects of statins." Ezetimibe oral tablet is a prescription medication used to reduce high cholesterol levels. Most people return to their pre-bypass level of function between 3 and 12 weeks after surgery. 3) Statins have not been shown to signicantly reduce the risk of heart disease. Drug information provided by: IBM Micromedex. A case of spontaneous biceps tendon rupture developed in a patient after 4 months of treatment with ezetimibe-simvastatin. So only 1 person out of 100 saw some benefit. Merck & Company Inc, West Point, PA. 6. "Product Information. Following discontinuation of ezetimibe-simvastatin, pain resolved 2 weeks later. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. J Neurol Neurosurg Psychiatry 58 (1995): 625-8, 44. In addition to diarrhea, joint pain and tiredness, patients have experienced severe muscle problems, especially when Zetia was added to complement the statin drug they were on. In some cases, you may need to be on some sort of cholesterol lowering medication, but it’s important to note that most people do not fall into that category, despite what doctors will have you believe. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. 5. Not likely. These side effects may go away during treatment as your body adjusts to the medicine. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances. Side Effects. So the bottom line here is don’t just take a drug blindly without learning more about it. Rashes, lesions, alterations in blood tests, liver problems, stomach pain, pancreas inflammation, nausea, depression, hair loss, gallstones and inflammation of the gall bladder have all been experienced. fever. Learn about side effects, warnings, dosage, and more. In Fiscal Year zetia memory loss Zetia and Vytorin reached for dyslipidemia (i. English Arabic Chinese (Simple) Precautions Korean Polish Portuguese (Brazilian) Russian Spanish Tagalog Vietnamese ) and when the ( 3 X ULN) or 4 hours zetia memory loss taking the acid sequestrant. Chan MH, Mak TW, Chiu RW, Chow CC, Chan IH, Lam CW "Simvastatin increases serum osteocalcin concentration in patients treated for hypercholesterolaemia." Upon rechallenge 2 months later, the patient developed pain in the contralateral arm overlying the biceps tendon. JAMA 275 (1996): 55-60, 48. AIDS 15 (2001): 1747-8, 17. Four months later, the patient's hemoglobin was stable. These reports have been generally nonserious, and reversible upon statin discontinuation, with variable times to symptom onset (1 day to years) and symptom resolution (median of 3 weeks). Lancet 341 (1993): 114. Data sources include IBM Watson Micromedex (updated 2 Nov 2020), Cerner Multum™ (updated 2 Nov 2020), ASHP (updated 23 Oct 2020) and others. Mauro VF, MacDonald JL "Simvastatin: a review of its pharmacology and clinical use." The reason for this is quite simple. hoarseness. The ingredients of this special formula have been shown to be much safer than the statin medications prescribed by many doctors. Abdominal or stomach fullness. Am J Med 110 (2001): 716-23, 47. Shah B, McAllister A, Davidson TM "Increased epistaxis with use of ezetimibe / simvastatin." Davidson MH, Maccubbin D, Stepanavage M, Strony J, Musliner T "Striated muscle safety of ezetimibe / simvastatin (vytorin)." Memory loss isn’t a side effect of Zetia. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them: The more commonly reported adverse effects have included headache, increased ALT, myalgia, upper respiratory tract infection, and diarrhea. indigestion. Doesn’t that sound better than being dependent on a prescription drug for the rest of your life? Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. South Med J 94 (2001): 1023-6, 11. van Puijenbroek EP, Du Buf-Vereijken PW, Spooren PF, van Doormaal JJ "Possible increased risk of rhabdomyolysis during concomitant use of simvastatin and gemfibrozil." hives. The patient reported initiation of ezetimibe-simvastatin as the only change in his treatment regimen in the past year. Lancet 344 (1994): 1383-9, 40. ... memory loss nightmares swelling of the breasts or breast soreness in both females and males unsteadiness or awkwardness weakness … Feldmann R, Mainetti C, Saurat JH "Skin lesions due to treatment with simvastatin (Zocor)." Ann Intern Med 137 (2002): 617-8, 24. What is the MCV Blood Test and What Does it Indicate? The doc said Zetia was different and wouldn’t cause those kinds of side effects. Neurology 58 (2002): 1333-7, 45. See the “Mild side effects” and “Serious side effects” sections above for more information. Available for Android and iOS devices. Maxa JL, Melton LB, Ogu CC, Sills MN, Limanni A "Rhabdomyolysis after concomitant use of cyclosporine, simvastatin, gemfibrozil, and itraconazole." Pedersen TR, Berg K, Cook TJ, Faergeman O, Haghfelt T, Kjekshus J, Miettinen T, Musliner TA, Olsson AG, Pyorala K, Thorgeirsso "Safety and tolerability of cholesterol lowering with simvastatin during 5 years in the scandinavian simvastatin survival study." Gaist D, Jeppesen U, Andersen M, Garcia Rodriguez LA, Hallas J, Sindrup SH "Statins and risk of polyneuropathy: a case-control study."