The conclusion reached as a result of this study is that Jelene is preferable to petrolatum because of its high stability over a wide temperature range. There are five (5) classes or types of ointment bases which are differentiated on the basis of their physical composition. Ointment Base Characteristics Examples; Oleaginous/Hydrocarbon Base: Occlusive, Greasy, Emollient, Not Water Washable, Will Not Absorb Water, Insoluble in Water Jelene 50W allows the preparation of physically superior ointments in most of those studied. - Non- ionic emulsifier. Hydrocarbon bases can remain on the skin for prolonged periods of time without drying out III. White petrolatum is the most common hydrocarbon base. The following statement/s is/are true for ointment base: I. Water-soluble bases have the ability to absorb serous discharges II. :- cationic emulsifier. Joseph Rodriguez • Example :- Emulsifying ointment B.P. [email protected]. Oleaginous bases are expected to provide a film, which resists soap and water yet readily removable by solutions of surfactants. 3. Questions: 1. Asst. Name Ointment Bases Accession Number DBCAT002024 Description. A new ointment base consisting essentially of saturated hydrocarbons is reported. Davis & Co. We use cookies to help provide and enhance our service and tailor content and ads. It has high stability over a wide range of temperature. 2. Cetomacrogel Emulsifying ointment B.P. A new ointment base known as Jelene 50W and consisting essentially of saturated hydrocarbons has been used in place of petrolatum as an ingredient of the bases for several official and unofficial ointments. (a) Water-in-oil type emulsion (Hydrophobic ointment): The w/o type emulsion bases such as lanolin and cold cream are used as emollients. The aqueous phase hydrates the skin and the oily phase forms an occlusive covering which prevents loss of water by evaporation. 1951 Oct;40(10):509-10. ). SOC.E x p f l . Second, ointment bases have conveniently been grouped into classes that generally define their properties; knowledge about these class traits helps greatly in selecting an appropriate base for a particular use. JONES ER, LEWICKI B. PMID: 14907445 The most important role of an ointment base is to allow the release of the active ingredient.3 In a test studying the release properties of antibiotics, researchers compared the results of using hydrocarbon gel versus white petrolatum. A new hydrocarbon ointment base; Jelene 50W. Other hydrocarbon bases include white ointment, yellow ointment, and yellow petrolatum. 73. All rights reserved. Copyright © 2020 COEK.INFO. ScienceDirect ® is a registered trademark of Elsevier B.V. ScienceDirect ® is a registered trademark of Elsevier B.V. A New Hydrocarbon Ointment Base: Jelene 50W. PMID: 14389902 No abstract available. 1. A. I only B. I & II C Ointments thus prepared have been compared over a period of several months with the same ointments containing petrolatum. Ointment bases recognized for use as vehicles fall into four general classes: the hydrocarbon bases, the absorption bases, the water-removable bases, and the water-soluble bases. 1955 Jul;40(3):86-9. They are non-water washable. Plastibase, a hydrocarbon gel ointment base Bull Sch Med Univ Md. Hydrocarbon Bases. Second, ointment bases have conveniently been grouped into classes that generally define their properties; knowledge about these class traits helps greatly in selecting an appropriate base for a particular use. Plastibase, a hydrocarbon gel ointment base. SCIENTIFIC EDITION Polyethylene glycol Ointment, NF is: 74. These are the earliest ointment bases which consisted of vegetable and animal fats as well as petroleum hydrocarbons. By continuing you agree to the use of cookies. Published by Elsevier Inc. All rights reserved. (13) Aadrews, E..Aronsohn, H. G., Proc. Ointments thus prepared have been compared over a period of several months with the same ointments containing petrolatum. 4. Give different ointment bases with examples. Copyright © 2020 Elsevier B.V. or its licensors or contributors. Ointment Bases. Ointments thus prepared have been compared over a period of several months with the same ointments containing petrolatum. Hydroxystearic Acid*, Simvastatin ointment, a new treatment for skin inflammatory conditions, A Comparative Analysis of Ointment Base Efficiency Utilizing a Pain Threshold Method*, Learn how we and our ad partner Google, collect and use data. Various mixtures of fats, waxes, animal and plant oils and solid and liquid hydrocarbons; vehicles for medicinal substances intended for external application; there are four classes: hydrocarbon base, absorption base, water-removable base and water-soluble base; several are also emollients. 1. (12) Neubauer. These bases are used for their emollient effect and are occlusive. • They are miscible with an excess of water ointment made from water miscible bases are easily remove after use. Author R C ROBINSON. (98)[8] 3. 2. Capacity of various ointment bases to absorb solvents. V. Jellified Ointments*, Hydrogenated Castor Oil as an Ointment Base. PDF | On Jan 1, 2009, Melgardt M De Villiers published Ointment Bases | Find, read and cite all the research you need on ResearchGate These ointment bases are referred to as “greaseless” bases. • There are three official anhydrous Water miscible ointment base. Most oils mix easily with hydrocarbon bases, but they reduce the viscosity of the preparation. Our partners will collect data and use cookies for ad personalization and measurement. A New Hydrocarbon Ointment Base: Jelene 50W, Sulfated Hydrogenated Castor Oil makes A Water-Soluble Ointment Base, Hydrogenated Castor Oil as an Ointment Base. E.. Klin. Address: October, 1951 Define and differentiate between Ointment and creams, lotion and liniment. Each therapeutic ointment possesses as its base a representative of one of these four general classes. (1) Hydrocarbon bases absorb no water and only very limited amounts of alcoholic solutions. Director, Products Development, Parke. Based on their makeup, ointment bases have varying capacities to absorb liquids. This base, Jelene 50W, has been substituted for the bases of 13 official ointments and the new and t h e official preparations have been studied under various conditions. A new ointment base known as Jelene 50W and consisting essentially of saturated hydrocarbons has been used in place of petrolatum as an ingredient of the bases for several official and unofficial ointments. A list of commonly used materials has been given here although in practice still a larger number of materials are used. Water-removable bases can also be called as water-soluble bases. J Am Pharm Assoc Am Pharm Assoc. (98) [4+4] 2. :- anionic emulsifier, ceterimide Emulsifying ointment B.P. Wochschr., 2 , 1065(1923). Preparation and preservation of these ointments with industrial equipment used for processing. 50 9 These bases are chemically inert and may be useful in preparing ointments containing water-insoluble or water-incompatible drugs. … Journal of the American Pharmaceutical Association (Scientific ed. A new ointment base known as Jelene 50W and consisting essentially of saturated hydrocarbons has been used in place of petrolatum as an ingredient of the bases for several official and unofficial ointments. IV. Copyright © 1951 Wiley-Liss, Inc., A Wiley Company. Ointment bases: oleaginous bases, hydrocarbon and silicon containing bases. Absorption bases, emulsion bases, water soluble bases.